GATOR1 Genetic Epilepsy Specialty Program
GATOR1 Genetic Epilepsy Specialty Program
Welcome to the GATOR1 Genetic Epilepsy Specialty Program. We are dedicated to provide high-quality care to patients with epilepsy caused by changes in the DEPDC5, NPRL2, and NPRL3 genes. Our expert team offers a comprehensive approach to care, research, and support to enhance the quality of life for our patients.
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Welcome to the GATOR1 Genetic Epilepsy Specialty Program. We are dedicated to provide high-quality care to patients with epilepsy caused by changes in the DEPDC5, NPRL2, and NPRL3 genes. Our expert team offers a comprehensive approach to care, research, and support to enhance the quality of life for our patients.
About GATOR1 Complex-Related Epilepsy
The GATOR1 complex is made up of three proteins, which are encoded by the DEPDC5, NPRL2, and NPRL3 genes. The GATOR1 complex helps regulate cell growth and brain activity. When the GATOR1 complex is unable to function properly, it can lead to difficult-to-control epilepsy and, in some cases, brain structural changes and cognitive challenges.Our mission
We are dedicated to delivering personalized care to individuals affected by GATOR1 complex-related epilepsy, with the goal of controlling seizures and advancing potential cures. Our approach centers on developing customized treatment plans, offering expert genetic counseling, and remaining at the cutting edge of epilepsy research.6410 Fannin St.
Suite 500 - Pediatric Care
Suite 1014 - Adult Care
Houston, TX 77030
Fax: (713) 383-1437
Parking available at the UTHealth Houston Garage, 6414 Fannin St.
Valet parking is also available.
How we can support you
Comprehensive evaluations (phase 1 and phase 2)
We do thorough evaluations to understand each patient’s epilepsy. In phase 1, we use diagnostic tools such as video-EEG, advanced MRI scans, and cognitive tests to track seizures and assess brain function. Wherever necessary, phase 2 involves more detailed tests, including invasive EEG monitoring and brain mapping, to pinpoint the exact location of seizures.
Surgical care
Based on these evaluations, we create personalized treatment plans. If surgery is needed, options may include procedures such as resective surgery or neuromodulation therapies such as vagus nerve stimulation (VNS), responsive neural stimulation (RNS), or deep brain stimulation (DBS).
Genetic counseling
Our genetic counselors help you understand your diagnosis and its implications for your family. They work alongside a team of genetics research experts who provide insights into variant interpretation.
Multidisciplinary team approach
Our clinic brings together experts from different fields, including neurology, genetics, and psychology, to ensure you get the best care possible. We tailor your visit based on your needs to provide comprehensive support.
Personalized treatment plans
Treatment plan will be informed by the latest information on GATOR1 complex-related epilepsy. This will include a personalized plan for managing seizures, enhancing quality of life, and addressing any comorbidities, whether present or emerging.
Patient and family resources
- Educational materials
We provide easy-to-understand information about GATOR1 complex-related epilepsy, treatment options, and current research to help you and your family. - Support groups
Connect with others going through similar experiences by joining our support groups. Share stories, seek advice, and find a supportive community. - Patient portal
Manage your care online through the MyUTHealth Houston patient portal. You can view your medical records, communicate with your care team, and schedule appointments.
Clinical research opportunities
We offer opportunities to participate in research studies focused on GATOR1 complex-related epilepsy. Our research aims to:
- Understand how genetic changes contribute to epilepsy.
- Test the effectiveness of various new treatments.
- Develop new tools to predict how the disease will progress and respond to treatment.
- Utilize the latest wearable technology to collect biological data, such as heart rate, blood oxygen levels, and respiratory rate, to investigate possible biomarkers for seizures.
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