Pancreatic Cancer
What is pancreatic cancer?
Pancreatic cancer occurs when abnormal cells grow out of control and form a tumor on the pancreas, a gland located deep in the abdomen that plays an important role in digestion and blood sugar regulation. Because the pancreas sits behind other organs, pancreatic cancer often does not cause symptoms in its early stages. Many people are diagnosed after the disease has begun to grow or spread. When found early, pancreatic cancer may be treated successfully with surgery, chemotherapy, radiation therapy, or a combination of these approaches. At UTHealth Houston Gastroenterology & Digestive Health, our multidisciplinary team works together to provide timely diagnosis, personalized treatment, and comprehensive support for patients and their families.
The most common type of pancreatic cancer is pancreatic ductal adenocarcinoma, which begins in the ducts of the pancreas. Less common tumors include pancreatic neuroendocrine tumors and certain cystic tumors that can become cancerous over time. Your care team will determine the exact type of tumor and create a treatment plan based on your individual diagnosis.
Risk factors for pancreatic cancer
Some people diagnosed with pancreatic cancer have no known risk factors. However, certain conditions and lifestyle factors may increase risk. These include smoking, diabetes, obesity, chronic pancreatitis, older age, and a family history of pancreatic cancer. Some inherited genetic syndromes are also associated with a higher risk. If you have a strong family history or a known genetic condition, our specialists can help determine whether screening is appropriate.
Symptoms of pancreatic cancer
Symptoms are often subtle at first and may be caused by many different conditions. Possible warning signs include yellowing of the skin or eyes, abdominal or back pain, unexplained weight loss, loss of appetite, nausea, vomiting, dark urine, pale stools, fatigue, or new-onset diabetes. These symptoms should be evaluated by a medical professional.
Diagnosis of pancreatic cancer
Pancreatic cancer is typically diagnosed using a combination of advanced imaging and specialized procedures. This may include CT scans, MRIs, endoscopic ultrasound, and endoscopic retrograde cholangiopancreatography. A biopsy is often performed to confirm the diagnosis, and blood tests may provide additional information. Our team uses the latest diagnostic technology to detect pancreatic cancer, determine its stage, and guide treatment planning as accurately as possible.
Treatment of pancreatic cancer
Treatment depends on the type of tumor, the stage of the disease, whether the cancer can be removed surgically, and your overall health and personal goals. Surgery typically offers the best chance for long-term survival when the tumor can be removed. Depending on the location of the cancer, procedures may include the Whipple procedure, distal pancreatectomy, or a total pancreatectomy.
Chemotherapy may be used before surgery to shrink a tumor, after surgery to reduce the risk of recurrence, or as the primary treatment when surgery is not possible. Radiation therapy is sometimes combined with chemotherapy to help control the disease. Some patients benefit from targeted therapies based on the genetic features of their tumor. Clinical trials may provide access to promising new treatment options.
Pancreatic cancer can affect digestion, nutrition, and bile flow. Our specialists offer advanced endoscopic and supportive treatments to relieve symptoms and improve quality of life. These therapies can help manage jaundice, control pain, support nutrition, and treat blockages in the stomach or small intestine.
Why choose UTHealth Houston?
Our program offers comprehensive diagnostic evaluation, multidisciplinary tumor board review, and advanced endoscopic procedures. We bring together experts in gastroenterology, oncology, radiology, pathology, genetics, and nutrition to create a coordinated, patient-centered treatment plan. We focus on rapid access to care, the most advanced diagnostic and therapeutic techniques, and personalized treatment based on your condition. We provide compassionate support for you and your family at every stage.