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Researchers discover lack of a protein could be the key to Alzheimer’s disease

New research shows a lack of a protein in the brain that keeps our tissues healthy as we age is linked to Alzheimer’s disease. (Photo by Getty Images)

A lack of a protein in the brain that keeps our tissues healthy as we age is linked to Alzheimer’s disease, according to recent research from The University of Texas Health Science Center at Houston (UTHealth).

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  • Researchers receive DOD funding to expand study of investigational drug to prevent ARDS in COVID-19 patients Photo of Ben Bobrow, MD, and Holger Eltzschig, MD, PhD, using the hypoxia chamber, which helped them discover that HIF activators could potentially treat damaged lungs. (Photo credit: Cody Duty/UTHealth)

    Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients were awarded $5.1 million in funding from the U.S. Department of Defense (DOD) to expand the Phase II clinical trial at UTHealth. 

  • Gene pathway linked to schizophrenia identified through stem cell engineering Image of neurons derived from induced pluripotent stem cells from a schizophrenia patient. (Photo by Laura Stertz, PhD/UTHealth)

    Using human-induced pluripotent stem cells engineered from a single family’s blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at UTHealth. The research was published in a recent issue of Neuropsychopharmacology.

  • Aging, diet-induced obesity, and metabolic disease link explored in new research Photograph of researcher Mikhail Kolonin, PhD, who led a study showing a link among aging, obesity, and metabolic disease. Photo credit is UTHealth.

    Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science Center at Houston (UTHealth).

  • Researchers discover brain pattern that could improve mental health disorder diagnosis and treatment Foods for Improving Mental Health and Wellness

    A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at UTHealth. The finding, which could help physicians more accurately diagnose and treat several major mental health disorders, was recently published in Molecular Psychiatry.

  • Researchers assess regenerative patch for in utero minimally invasive surgery for spina bifida defect Photo of KuoJen Tsao, MD; Ramesha Papanna, MD, MPH; Stephen Fletcher, MD; and Clifton Brock, MD, practicing the fetoscopic surgery. (Photo credit: Ramesha Papanna, MD, MPH)

    Researchers are investigating whether a human umbilical cord patch placed on the spina bifida defect could improve healing after minimally invasive fetoscopic surgery in a clinical trial at The University of Texas Health Science Center at Houston (UTHealth).

  • Linking medically complex children’s outpatient team with hospitalists improved inpatient care Photo of Dr, Ricardo Mosquera assisting a child as she does a breathing test for a story about clinical providers linking with hospitalists. Photo by Dwight Andrews.

    When medically complex children are hospitalized, linking hospitalists to their regular outpatient providers through an inpatient consultation service were more likely to improve outcomes, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

  • Research unlocks new information about reading through visual dictionary in the brain Photo of Nitin Tandon, MD, who identified a crucial region in the temporal lobe which appears to act as the brain’s visual dictionary. (Photo by James LaCombe)

    The uniquely human ability to read is the cornerstone of modern civilization, yet very little is understood about the effortless ability to derive meaning from written words. Scientists at UTHealth have now identified a crucial region in the temporal lobe, know as the mid-fusiform cortex, which appears to act as the brain’s visual dictionary.

  • Patient with aortic aneurysm benefits from innovative, minimally invasive procedure Gustavo Oderich, MD, FACS, checks Rodolfo Sandoval’s heartbeat at his six-week post operation checkup. Oderich repaired Sandoval’s complex aortic aneurysm with a minimally invasive procedure. (Photo by: Caliann Ferguson/UTHealth)

    When Rodolfo Sandoval was told he would need to undergo open surgery to repair his thoracic and abdominal aortic aneurysm, he hesitated. At 73 years old, he was worried about the recovery process for a major, invasive procedure. Then COVID-19 arrived and he made the decision that he would only consider the surgery if it became a life or death situation.

  • Physicians investigate whether magnetic seizure therapy can treat bipolar depression Photo of Salih Selek, MD, who conducted magnetic seizure therapy (MST) in a clinical trial investigating whether the therapy can help relieve treatment-resistant depression in bipolar patients. (Photo by Maricruz Kwon/UTHealth)

    Researchers are assessing whether magnetic seizure therapy (MST) can help relieve treatment-resistant depression in bipolar patients in a clinical trial led by UTHealth. 

  • Neurologists test novel compound for lung and brain injury in severe COVID-19 patients Photo of how the investigational compound is designed to selectively attack the immune cells responsible for hyperinflammation, lung injury, and multi-organ failure caused by infections. (Photo credit: W20)

    Neurologists are researching whether a novel immunomodulatory treatment, OP-101, can dampen lung and brain injury in hospitalized COVID-19 patients through a clinical trial at The University of Texas Health Science Center at Houston (UTHealth).

  • Providing a safe environment for psychiatric patients during pandemic Photo of Doctor Lokesh Shahani and nurse Roshan Cherian wearing PPE to work in a special COVID-19 unit  at UTHealth Harris County Psychiatric Center. Photo by UTHealth.

    The very heart of inpatient care for psychiatric patients is socialization, group therapy, shared meals, and a standard two people per room. Then COVID-19 hit with the accompanying public health warnings to isolate, socially distance, and wear masks. UTHealth HCPC had to walk the line between the two.

  • Researchers seeking volunteers for COVID-19 vaccine study Carmel B. Dyer, MD, speaks to two trial participants at the UTHealth Clinical Research Unit at Memorial Hermann-Texas Medical Center. (Photo by: Roger Castro/UTHealth)

    A Phase III clinical trial to assess if a potential vaccine is effective at preventing symptomatic COVID-19 is now open for enrollment by The University of Texas Health Science Center at Houston (UTHealth) in collaboration with Memorial Hermann-Texas Medical Center.

  • Study seeks to help boost understanding of deep brain stimulation for essential tremor Photo of Albert Fenoy, MD, performing deep brain stimulation surgery (DBS) at Memorial Hermann-Texas Medical Center. He is now leading a new research study on DBS. (Photo by Memorial Hermann)

    A high-tech imaging study to understand how brain connectivity patterns change after deep brain stimulation in patients suffering from essential tremor has been launched at The University of Texas Health Science Center at Houston (UTHealth).

  • Researchers receive $3.1 million to fund four-dimensional work on Down syndrome Human Cell Illustration

    To better understand the molecular basis of Down syndrome, a genetic disease that affects 1 in 750 infants born in the U.S., researchers at The University of Texas Health Science Center at Houston (UTHealth) have received a $3.1 million grant from the National Institutes of Health (NIH).

     

  • Pregnant Hispanic patients more likely to contract COVID-19 than other racial-ethnic groups Photo of a pregnant women that says pregnant Hispanic women tested positive for COVID-19 at nearly twice the rate of other racial-ethnic groups. (Photo by Getty Images and Lauren Mathews/UTHealth)

    Pregnant Hispanic patients were nearly twice as likely to be diagnosed with COVID-19 than other racial-ethnic groups and most were asymptomatic, according to research by The University of Texas Health Science Center at Houston (UTHealth).

  • $3 million grant to further study how neurons work together Brain disease diagnosis

    Studying how neurons work together in order to better understand neurological disorders such as Alzheimer’s disease and autism spectrum disorders, researchers led by John Byrne, PhD, at The University of Texas Health Science Center at Houston (UTHealth) have been awarded more than $3 million from the National Institutes of Health BRAIN Initiative.

  • Researchers receive more than $53 million to study role of white matter lesions in dementia At Home Care Giver

    A $53.6 million grant from the National Institutes of Health will aid brain scientists, including a researcher from The University of Texas Health Science Center at Houston (UTHealth), in studying the role of incidental white matter lesions, or WMLs, in dementia among diverse people with cognitive complaints.

  • Pioneering research shows the benefits and risks of treating appendicitis with antibiotics instead of surgery appendicitis

    Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to researchers with The University of Texas Health Science Center at Houston (UTHealth), who led the Houston trial sites.

  • $5 million NIH grant awarded to reduce COVID-19-related disparities in vulnerable populations Photo of two nurses preparing for drive-thru testing at UT Physicians-Victory. Photo by Maricruz Kwon, UTHealth.

    To help reduce COVID-19-related health disparities in vulnerable populations in Texas, a multi-institutional team of researchers led by The University of Texas Health Science Center at Houston (UTHealth) will identify disease hotspots and testing deserts in three racially diverse areas, and then develop and evaluate intervention strategies to increase COVID-19 testing.

  • First Houston post-coronavirus clinic part of new UTHealth COVID-19 Center of Excellence Photo of UTHealth researchers and physicians, from left, Luis Ostrosky, MD; Bela Patel, MD; and Henry Wang, MD, MPH, are leading clinical trials on COVID-19. (Photo by Maricruz Kwon/UTHealth)

    Bringing together expertise and access to the best clinical care, research trials, discovery science, and public health knowledge, The University of Texas Health Science Center at Houston (UTHealth) has established the UTHealth COVID-19 Center of Excellence.

  • Researchers studying new nonsurgical treatment for chronic sinusitis Sneezing Woman

    Researchers at The University of Texas Health Science Center at Houston (UTHealth) are investigating the efficacy and safety of an intranasal treatment for adults with chronic sinusitis with or without nasal polyps.

  • Clinical trial to assess rehabilitation treatment for infants and toddlers after stroke Therapist Kelsey Burke of the Fralin Biomedical Research Institute Neuromotor Research Clinic works with a young patient using I-ACQUIRE therapy. (Photo by: Fralin Biomedical Research Institute)

    In the first of its kind for the tiniest stroke survivors, researchers at The University of Texas Health Science Center at Houston (UTHealth) will lead a stroke rehabilitation clinical trial in the state of Texas through a multi-institutional NIH StrokeNet initiative.

  • Placenta accreta month: Novel approach to life-threatening pregnancy condition allows woman to have “miracle child” after loss Placenta accreta patient, Margarita Saavedra Margarita Saavedra was 35 years old and 18 weeks pregnant with her second child when she fainted at the doctor’s office after receiving the news that she might need to have a hysterectomy to remove her uterus.
  • Could the time of day impact the effectiveness of COVID-19 treatment? Medication Time

    For months, experts have warned against the use of anti-inflammatory medications, such as ibuprofen, to treat COVID-19 symptoms. But could the timing of when this drug is taken play a role in its effectiveness?

  • Young Houston woman recovers from COVID-19 after participation in two UTHealth clinical trials Photo of Bindu Akkanti, MD, who discusses the benefit of academic medicine after one of her patients, who was enrolled in two clinical trials, recovers from COVID-19. (Photo credit: Bindu Akkanti, MD) Heba Hajjar, 23, recovered from COVID-19 after participating in two clinical trials through The University of Texas Health Science Center at Houston (UTHealth) while in the intensive care unit (ICU) at Memorial Hermann-Texas Medical Center. She was so weak she couldn’t move or sit up in bed. She was cautiously monitored on oxygen therapy and […]
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